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Methyl 7-aminothieno[2,3-b]pyrazine-6-carboxylate

  • CAS No. 244014-85-5

  • Cat. No. CS-0144027
  • Purity≥98%
  • MDL No.MFCD00204059

*For research and further manufacturing use only, not for direct human use.

Methyl 7-aminothieno[2,3-b]pyrazine-6-carboxylate|CS-0144027

Structure of 244014-85-5

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General Information

  • CAS No. 244014-85-5
  • Cat. No. CS-0144027
  • Purity ≥98%
  • MDL No. MFCD00204059
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇N₃O₂S
  • Molecular Weight 209.23
  • Synonym(s) Thieno[2,3-b]pyrazine-6-carboxylic acid, 7-amino-, methyl ester (9CI)
  • SMILES O=C(C1=C(N)C2=NC=CN=C2S1)OC

Description

Methyl 7-aminothieno[2,3-b]pyrazine-6-carboxylate features a fused thienopyrazine core with a strategically positioned amino group enabling direct functionalization. The ester moiety supports derivatization under standard conditions, while the electron-rich heterocycle enhances reactivity in cross-coupling and cyclization processes. This scaffold offers robust stability and solubility in polar organic solvents, facilitating integration into complex molecular architectures.

Application

Methyl 7-aminothieno[2,3-b]pyrazine-6-carboxylate serves as a versatile building block for the synthesis of thienopyrazine-based heterocycles. The amino and ester functionalities enable selective derivatization via acylation, alkylation, or coupling reactions, facilitating access to diverse scaffolds relevant in medicinal chemistry. Its bench-stable nature and compatibility with standard purification methods support reliable use in multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   78.1
  • LogP   1.0601
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   1

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