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CS-W001157 4
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Cyclopentylhydrazine hydrochloride

  • CAS No. 24214-72-0

  • Cat. No. CS-D0525
  • Purity≥95%
  • MDL No.MFCD01320505

*For research and further manufacturing use only, not for direct human use.

Cyclopentylhydrazine hydrochloride|CS-D0525

Structure of 24214-72-0

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General Information

  • CAS No. 24214-72-0
  • Cat. No. CS-D0525
  • Purity ≥95%
  • MDL No. MFCD01320505
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₃ClN₂
  • Molecular Weight 136.62
  • Synonym(s) cyclopentylhydrazine HCl
  • SMILES NNC1CCCC1.Cl

Description

Cyclopentylhydrazine hydrochloride offers a stable, moisture-tolerant platform for constructing hydrazone derivatives in synthetic and medicinal chemistry. The cyclopentyl ring imparts conformational rigidity, enhancing target selectivity in bioactive molecule design. This bench-stable salt facilitates straightforward handling and integration into multistep syntheses under standard conditions.

Application

Cyclopentylhydrazine hydrochloride serves as a reliable building block for the synthesis of hydrazone derivatives and heterocyclic scaffolds, particularly in medicinal chemistry applications. Its bench-stable nature and high functional group tolerance facilitate straightforward incorporation into diverse reaction workflows. The compound enables efficient access to bioactive frameworks through standard condensation protocols and functions effectively in both small-molecule library construction and target-oriented synthesis.

Synthesis

  • Route1
    • Tert-butyl 2-cyclopentylidenehydrazine-1-carboxylate|CS-0466458
      79201-39-1
    • ~99%
    • In-stock
      Cyclopentylhydrazine hydrochloride|CS-D0525
      24214-72-0

    References

    • Anderson, Kevin William; Fotouhi, Nader; Gillespie, Paul; Goodnow, Robert Alan; Guertin, Kevin Richard; Haynes, Nancy-Ellen; Myers, Michael Paul; Pietranico-Cole, Sherrie Lynn; Qi, Lida; Rossman, Pamela Loreen; Scott, Nathan Robert; Thakkar, Kshitij Chhabilbhai; Tilley, Jefferson Wright; Zhang, Qiang Patent: US2007/225280 A1, 2007 ; Location in patent: Page/Page column 48 ; US 20070225280 A1
  • Route2
    • tert-Butyl 2-cyclopentylhydrazinecarboxylate|CS-0054989
      646071-31-0
    • ~%
    • In-stock
      Cyclopentylhydrazine hydrochloride|CS-D0525
      24214-72-0

    References

    • Journal of Organic Chemistry, , vol. 46, # 26 p. 5413 - 5414
  • Route3
    • null|null
      120-92-3
    • ~%
    • In-stock
      Cyclopentylhydrazine hydrochloride|CS-D0525
      24214-72-0

    References

    • Journal of Organic Chemistry, , vol. 46, # 26 p. 5413 - 5414

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   0.8141
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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