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CS-W001157 4
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Cyclobutylhydrazine hydrochloride

  • CAS No. 158001-21-9

  • Cat. No. CS-D1710
  • Purity≥95%
  • MDL No.MFCD06658415

*For research and further manufacturing use only, not for direct human use.

Cyclobutylhydrazine hydrochloride|CS-D1710

Structure of 158001-21-9

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General Information

  • CAS No. 158001-21-9
  • Cat. No. CS-D1710
  • Purity ≥95%
  • MDL No. MFCD06658415
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₁ClN₂
  • Molecular Weight 122.60
  • Synonym(s) N-Cyclobutylhydrazine HCl
  • SMILES NNC1CCC1.[H]Cl

Description

Cyclobutylhydrazine hydrochloride offers a rigid, strain-bearing cyclobutyl scaffold fused to a hydrazine moiety, enabling precise spatial control in nitrogen-rich heterocycle synthesis. This bench-stable salt delivers enhanced reactivity in transition-metal-catalyzed coupling processes and serves as a key intermediate in the development of bioactive small molecules.

Application

Cyclobutylhydrazine hydrochloride serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds through hydrazone formation and subsequent cyclization. Its bench-stable nature and compatibility with common functional groups facilitate straightforward incorporation into complex molecules. The compound functions effectively in standard coupling protocols and offers reliable reactivity for nitrogen-directed transformations in API development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H335
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   0.424
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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