Lot numbers can be found on the outside label of a product:
(S)-5-hydroxypiperidin-2-one
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CAS No. 24211-54-9
- Cat. No. CS-D0042
- Purity≥96%
- MDL No.MFCD06202374
*For research and further manufacturing use only, not for direct human use.
Structure of 24211-54-9
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General Information
- CAS No. 24211-54-9
- Cat. No. CS-D0042
- Purity ≥96%
- MDL No. MFCD06202374
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₅H₉NO₂
- Molecular Weight 115.13
- Synonym(s) (S)-5-HYDROXY-PIPERIDIN-2-ONE
- SMILES O=C1NC[C@@H](O)CC1
Description
(S)-5-Hydroxypiperidin-2-one is a chiral heterocyclic scaffold featuring a hydroxyl group at the C5 position and a carbonyl at C2, enabling selective functionalization in asymmetric synthesis. This bench-stable building block integrates readily into medicinal chemistry campaigns targeting CNS therapeutics and peptide mimetics, where stereochemical control is critical.
Application
(S)-5-Hydroxypiperidin-2-one serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to saturated heterocycles and bioactive scaffolds. Its well-defined stereochemistry and orthogonal functional groups facilitate selective transformations, including derivatization at the hydroxyl and carbonyl sites. The compound exhibits good bench stability and is compatible with standard synthetic protocols, supporting its use in API development and route optimization.
Synthesis
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Route1
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24211-53-8 - ~94%
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In-stock
24211-54-9
References
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Huh, Nam; Thompson, Charles M. Tetrahedron, 1995 , vol. 51, # 21 p. 5935 - 5950
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Route2
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1179999-39-3 - ~85%
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In-stock
24211-54-9
References
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Spangler, Kimberly Yearick; Wolf, Christian Organic Letters, 2009 , vol. 11, # 20 p. 4724 - 4727
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Route3
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58879-34-8 - ~%
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In-stock
24211-54-9
References
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Tetrahedron Asymmetry, , vol. 7, # 6 p. 1811 - 1818
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 49.33
- LogP -0.7427
- H_Acceptors 2
- H_Donors 2
- Rotatable_Bonds 0
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Key Words
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