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Structure of 1073182-59-8
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Methyl 5-amino-2-chloroisonicotinate features a strategically positioned amino group and chlorine atom on the pyridine ring, enabling selective coupling reactions in medicinal chemistry. This bench-stable derivative integrates readily into heterocyclic scaffolds, offering enhanced solubility and reactivity under standard conditions.
Methyl 5-amino-2-chloroisonicotinate serves as a versatile building block in medicinal chemistry, enabling direct access to substituted isonicotinamide scaffolds. Its amino and chloro groups offer orthogonal reactivity for late-stage functionalization via Suzuki-Miyaura coupling or amide formation. The methyl ester facilitates straightforward derivatization, while the compound exhibits excellent bench stability and ease of purification—ideal for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: