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CS-W001157 4
Total: USD 88.00

5-Hydroxypiperidin-2-one

  • CAS No. 19365-07-2

  • Cat. No. CS-D0057
  • Purity≥97%
  • MDL No.MFCD02258339

*For research and further manufacturing use only, not for direct human use.

5-Hydroxypiperidin-2-one|CS-D0057

Structure of 19365-07-2

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General Information

  • CAS No. 19365-07-2
  • Cat. No. CS-D0057
  • Purity ≥97%
  • MDL No. MFCD02258339
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉NO₂
  • Molecular Weight 115.13
  • Synonym(s) 5-Hydroxy-Piperidin-2-One
  • SMILES O=C1NCC(O)CC1

Description

5-Hydroxypiperidin-2-one features a cyclic amide core with a hydroxyl group at the 5-position, offering enhanced polarity and hydrogen-bonding capacity. This structural motif enables efficient incorporation into bioactive molecules, particularly in medicinal chemistry scaffolds requiring solubility and metabolic stability. The compound serves as a versatile building block for targeted synthesis under standard conditions.

Application

5-Hydroxypiperidin-2-one serves as a versatile scaffold in medicinal chemistry, enabling efficient access to diverse heterocyclic systems through its amide and hydroxyl functionalities. Its stability under standard reaction conditions facilitates straightforward functionalization, while the orthogonality of its carbonyl and hydroxyl groups supports selective derivatization in multi-step synthesis. Widely employed in API development, it functions as a key building block for bioactive molecules requiring constrained piperidine frameworks with tailored polarity and hydrogen-bonding capacity.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   -0.7427
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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