Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1,2-Dichloro-3-iodobenzene

  • CAS No. 2401-21-0

  • Cat. No. CS-W014026
  • Purity≥98%
  • MDL No.MFCD00001034

*For research and further manufacturing use only, not for direct human use.

1,2-Dichloro-3-iodobenzene|CS-W014026

Structure of 2401-21-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 2401-21-0
  • Cat. No. CS-W014026
  • Purity ≥98%
  • MDL No. MFCD00001034
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃Cl₂I
  • Molecular Weight 272.89
  • Synonym(s) 2,3-Dichloroiodobenzene; 1,2-Dichloro-3-iodobenzene
  • SMILES IC1=C(Cl)C(Cl)=CC=C1

Description

1,2-Dichloro-3-iodobenzene is a halogenated aromatic compound featuring complementary chlorine and iodine substituents at adjacent positions on the benzene ring. This configuration enables selective cross-coupling reactions in transition-metal-catalyzed processes, particularly in palladium-mediated C–C bond formation. The molecule's electron-deficient nature enhances reactivity in Suzuki-Miyaura and Stille couplings while maintaining stability under standard reaction conditions.

Application

1,2-Dichloro-3-iodobenzene serves as a versatile building block in cross-coupling chemistry, enabling the construction of substituted biaryls and heterocycles under palladium-catalyzed conditions. The ortho-dichloro substitution pattern provides enhanced stability and facilitates selective functionalization, while the iodine moiety offers high reactivity in Suzuki, Stille, and Negishi couplings. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for iterative synthesis workflows in medicinal chemistry and materials science.

Synthesis

  • Route1
    • null|null
      95-50-1
    • ~72%
    • In-stock
      1,2-Dichloro-3-iodobenzene|CS-W014026
      2401-21-0

    References

    • Naka, Hiroshi; Uchiyama, Masanobu; Matsumoto, Yotaro; Wheatley, Andrew E. H.; McPartlin, Mary; Morey, James V.; Kondo, Yoshinori Journal of the American Chemical Society, 2007 , vol. 129, # 7 p. 1921 - 1930
  • Route2

    References

    • American Cyanamid Company Patent: US4203918 A1, 1980 ; Title/Abstract Full Text Show Details American Cyanamid Co. Patent: US4358607 A1, 1982 ;
  • Route3
    • null|null
      608-27-5
    • ~%
    • In-stock
      1,2-Dichloro-3-iodobenzene|CS-W014026
      2401-21-0

    References

    • Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 1593 - 1598

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   0
  • LogP   3.598
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1,2-Dichloro-3-iodobenzene sigma1,2-Dichloro-3-iodobenzene manufacturer1,2-Dichloro-3-iodobenzene price1,2-Dichloro-3-iodobenzene structure1,2-Dichloro-3-iodobenzene SDSbuy 1,2-Dichloro-3-iodobenzene1,2-Dichloro-3-iodobenzene supplier1,2-Dichloro-3-iodobenzene uses1,2-Dichloro-3-iodobenzene molecular weightprice of 1,2-Dichloro-3-iodobenzene1,2-Dichloro-3-iodobenzene chemical name formula of 1,2-Dichloro-3-iodobenzene
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label