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CS-W001157 4
Total: USD 88.00

3,3'-Oxybis(propan-1-ol)

  • CAS No. 2396-61-4

  • Cat. No. CS-0131092
  • Purity≥97%
  • MDL No.MFCD00051023

*For research and further manufacturing use only, not for direct human use.

3,3'-Oxybis(propan-1-ol)|CS-0131092

Structure of 2396-61-4

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General Information

  • CAS No. 2396-61-4
  • Cat. No. CS-0131092
  • Purity ≥97%
  • MDL No. MFCD00051023
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄O₃
  • Molecular Weight 134.18
  • Synonym(s) 3,3'-Oxydipropanol
  • SMILES OCCCOCCCO

Description

3,3'-Oxybis(propan-1-ol) is a bifunctional diol featuring two primary hydroxyl groups flanking an ether linkage. This structure enables efficient coupling in polymer synthesis and provides enhanced solubility in polar solvents. The molecule demonstrates stability under standard handling conditions and serves as a key building block for tailored polyether architectures.

Application

3,3'-Oxybis(propan-1-ol) serves as a versatile diol building block for the synthesis of polyethers and functionalized polymers. Its two primary hydroxyl groups enable straightforward derivatization via esterification, etherification, or protection strategies, while the symmetric structure supports efficient coupling reactions. The molecule exhibits good bench stability and ease of purification, making it suitable for iterative synthesis workflows in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • Buchanan; Driega; Yap Canadian Journal of Chemistry, 2000 , vol. 78, # 3 p. 316 - 321
  • Route2
    • null|null
      635677-60-0
    • ~99%
    • In-stock
      3,3'-Oxybis(propan-1-ol)|CS-0131092
      2396-61-4

    References

    • Knuf, Erin C.; Jiang, Jian-Kang; Gin, Mary S. Journal of Organic Chemistry, 2003 , vol. 68, # 23 p. 9166 - 9169
  • Route3
    • null|null
      1656-48-0
    • ~64%
    • In-stock
      3,3'-Oxybis(propan-1-ol)|CS-0131092
      2396-61-4

    References

    • ESPERION THERAPEUTICS, INC. Patent: WO2005/68410 A1, 2005 ; Location in patent: Page/Page column 232 ; WO 2005/068410 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P302+P352

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   -0.2322
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   6

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