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CS-W001157 4
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H-Lys(Boc)-OMe hydrochloride

  • CAS No. 2389-48-2

  • Cat. No. CS-0005482
  • Purity≥97%
  • MDL No.MFCD00076959

*For research and further manufacturing use only, not for direct human use.

H-Lys(Boc)-OMe hydrochloride|CS-0005482

Structure of 2389-48-2

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General Information

  • CAS No. 2389-48-2
  • Cat. No. CS-0005482
  • Purity ≥97%
  • MDL No. MFCD00076959
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₅ClN₂O₄
  • Molecular Weight 296.79
  • Synonym(s) None
  • SMILES N[C@@H](CCCCNC(OC(C)(C)C)=O)C(OC)=O.[H]Cl

Description

H-Lys(Boc)-OMe hydrochloride is a protected lysine derivative featuring a tert-butoxycarbonyl group on the ε-amino function and a methyl ester at the C-terminus, enabling efficient incorporation into peptide chains. This bench-stable, moisture-tolerant building block simplifies purification and facilitates orthogonal deprotection strategies in solid-phase synthesis.

Application

H-Lys(Boc)-OMe hydrochloride serves as a versatile, bench-stable building block for peptide synthesis, enabling efficient incorporation of side-chain protected lysine residues. The Boc group provides orthogonal protection for the ε-amino function, while the methyl ester facilitates downstream derivatization. Its hydrochloride salt enhances solubility and handling, supporting reliable coupling in standard solid-phase and solution-phase protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   90.65
  • LogP   1.6035
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   6

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