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CS-W001157 4
Total: USD 88.00

2-Isopropylthiazole-4-carboxylic acid

  • CAS No. 234445-61-5

  • Cat. No. CS-W006653
  • Purity≥96%
  • MDL No.MFCD09055228

*For research and further manufacturing use only, not for direct human use.

2-Isopropylthiazole-4-carboxylic acid|CS-W006653

Structure of 234445-61-5

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General Information

  • CAS No. 234445-61-5
  • Cat. No. CS-W006653
  • Purity ≥96%
  • MDL No. MFCD09055228
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉NO₂S
  • Molecular Weight 171.22
  • Synonym(s) 4-Thiazolecarboxylicacid,2-(1-methylethyl)-(9CI)
  • SMILES CC(C)C1=NC(=CS1)C(O)=O

Description

2-Isopropylthiazole-4-carboxylic acid features a thiazole core functionalized with a carboxylic acid at the 4-position and a sterically hindered isopropyl group at the 2-position. This combination imparts enhanced solubility and metabolic stability, enabling efficient incorporation into bioactive scaffolds for medicinal chemistry applications.

Application

2-Isopropylthiazole-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of thiazole-based scaffolds prevalent in bioactive molecules. Its carboxylic acid functionality facilitates direct coupling reactions, while the isopropyl group enhances metabolic stability and modulates lipophilicity. The compound exhibits good bench stability and functional group tolerance, making it well-suited for iterative synthetic workflows and API intermediate development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.9647
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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