5-Bromo-2-methoxybenzenesulfonyl chloride

Name: 5-Bromo-2-methoxybenzenesulfonyl chloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 23095-05-8
Cat. No. CS-W010023
Purity≥95%
MDL No.MFCD00051768

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-methoxybenzenesulfonyl chloride|CS-W010023

Structure of 23095-05-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 23095-05-8
Cat. No. CS-W010023
Purity ≥95%
MDL No. MFCD00051768
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆BrClO₃S
Molecular Weight 285.54
Synonym(s) benzenesulfonyl chloride, 5-bromo-2-methoxy-; 5-Bromo-2-methoxybenzenesulfonyl chloride
SMILES O=S(C1=CC(Br)=CC=C1OC)(Cl)=O

Description

5-Bromo-2-methoxybenzenesulfonyl chloride features a brominated aromatic ring fused to a sulfonyl chloride group, enabling selective electrophilic functionalization. The methoxy substituent enhances solubility and modulates electronic effects, while the sulfonyl chloride moiety offers high reactivity in amide and sulfonamide synthesis under mild conditions.

Application

5-Bromo-2-methoxybenzenesulfonyl chloride serves as a versatile building block for sulfonamide synthesis, enabling efficient introduction of brominated and methoxy-substituted sulfonyl groups into bioactive molecules. Its reactivity is well-documented in late-stage functionalization and heterocycle construction, with predictable behavior in nucleophilic substitution reactions. The molecule exhibits bench stability and facilitates straightforward purification, making it suitable for scalable medicinal chemistry campaigns and API intermediate development.

Synthesis

Route1
- 104-92-7
- ~%
- In-stock
  
  23095-05-8
References
- Journal of the Chemical Society [Section] C: Organic, , p. 1341 - 1345
Route2
- In-stock
  
  6358-77-6
- ~%
- In-stock
  
  23095-05-8
References
- Journal of Medicinal Chemistry, , vol. 55, # 11 p. 5467 - 5482

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 3261
Class : 8	Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 43.37
LogP 2.3852
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

23095-05-8 sigma23095-05-8 manufacturer23095-05-8 price23095-05-8 structure23095-05-8 SDSbuy 23095-05-823095-05-8 supplier23095-05-8 uses23095-05-8 molecular weightprice of 23095-05-823095-05-8 chemical name formula of 23095-05-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Bromo-2-methoxybenzenesulfonyl chloride

CAS No. 23095-05-8

Recommended Products