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Structure of 226989-35-1
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1-Benzyl-1H-pyrazol-4-ol features a pyrazole core functionalized with a hydroxyl group at C4 and a benzyl substituent at N1, delivering enhanced solubility and metabolic stability. This scaffold integrates readily into bioactive molecule design, particularly in kinase inhibitors and antitumor agents, where its electron-rich heterocycle supports target engagement through hydrogen bonding and π-stacking interactions.
1-Benzyl-1H-pyrazol-4-ol serves as a versatile scaffold for constructing bioactive heterocycles, enabling efficient functionalization at the pyrazole C4 position. Its bench-stable nature and tolerance to common reaction conditions facilitate downstream derivatization in medicinal chemistry campaigns. Functions effectively as a building block in coupling reactions and transition-metal-catalyzed transformations, offering reliable access to substituted pyrazole derivatives with predictable reactivity profiles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: