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CS-W001157 4
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1-Methyl-1H-pyrazol-4-ol

  • CAS No. 78242-20-3

  • Cat. No. CS-0044173
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-Methyl-1H-pyrazol-4-ol|CS-0044173

Structure of 78242-20-3

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General Information

  • CAS No. 78242-20-3
  • Cat. No. CS-0044173
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆N₂O
  • Molecular Weight 98.10
  • Synonym(s) 1H-Pyrazol-4-ol,1-methyl
  • SMILES OC1=CN(C)N=C1

Description

1-Methyl-1H-pyrazol-4-ol features a pyrazole scaffold with a methyl group at N1 and a hydroxyl at C4, delivering enhanced solubility and stability. This electron-rich heterocycle integrates readily into medicinal chemistry scaffolds, offering a polar, hydrogen-bonding handle for molecular recognition and synthetic elaboration under standard conditions.

Application

1-Methyl-1H-pyrazol-4-ol serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles through standard functionalization protocols. Its pyrazole core exhibits favorable bench stability and compatibility with common coupling reactions, facilitating downstream derivatization. The compound functions as a key scaffold for kinase inhibitors and other pharmacologically relevant architectures, offering predictable reactivity and straightforward purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   0.1257
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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