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CS-W001157 4
Total: USD 88.00

Propylboronic acid

  • CAS No. 17745-45-8

  • Cat. No. CS-W007470
  • Purity≥98%
  • MDL No.MFCD01074564

*For research and further manufacturing use only, not for direct human use.

Propylboronic acid|CS-W007470

Structure of 17745-45-8

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General Information

  • CAS No. 17745-45-8
  • Cat. No. CS-W007470
  • Purity ≥98%
  • MDL No. MFCD01074564
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₉BO₂
  • Molecular Weight 87.91
  • Synonym(s) None
  • SMILES CCCB(O)O

Description

Propylboronic acid offers a stable, moisture-tolerant boronate handle for Suzuki-Miyaura cross-coupling reactions. This bench-stable reagent integrates readily into synthetic sequences, enabling efficient C–C bond formation under mild conditions. The propyl chain enhances solubility in organic media while maintaining high functional group compatibility.

Application

Propylboronic acid serves as a reliable building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its stability, ease of handling, and compatibility with diverse functional groups make it well-suited for the synthesis of alkyl-substituted arenes and heterocycles in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • null|null
      121-43-7
    • null|null
      927-77-5
    • ~55%
    • In-stock
      Propylboronic acid|CS-W007470
      17745-45-8

    References

    • Gmelin Handbook: B: SVol.1, 4.8.4, page 224 - 226
  • Route2
    • null|null
      19567-27-2
    • ~%
    • In-stock
      Propylboronic acid|CS-W007470
      17745-45-8
    • null|null
      11113-50-1

    References

    • Journal of the American Chemical Society, , vol. 58, p. 407
  • Route3
    • null|null
      1116-61-6
    • ~%
    • In-stock
      Propylboronic acid|CS-W007470
      17745-45-8

    References

    • DE371467 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 14, p. 1451

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   -0.1308
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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