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Structure of 22519-35-3
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7-Chloro-1,3-dioxaindane-5-carboxylic acid features a rigid, electron-deficient dioxaindane core that enhances metabolic stability and facilitates efficient coupling in synthetic transformations. This bench-stable scaffold integrates readily into complex molecular architectures, offering predictable reactivity under standard conditions.
7-Chloro-1,3-dioxaindane-5-carboxylic acid serves as a versatile building block for heterocyclic synthesis, particularly in the construction of biologically relevant indoline and indole scaffolds. The molecule combines a stable dioxane-fused indane core with a carboxylic acid functionality that enables direct coupling reactions or derivatization. Its chlorine substituent provides a handle for further functionalization via nucleophilic substitution or transition-metal-catalyzed processes. The compound exhibits good bench stability and facilitates straightforward purification, making it suitable for iterative synthetic campaigns in medicinal chemistry and process development.
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Lot numbers can be found on the outside label of a product: