(2S,3S)-3-(tert-Butyl)-4-(2,6-dimethoxyphenyl)-2-ethyl-2,3-dihydrobenzo[d][1,3]oxaphosphole

Name: (2S,3S)-3-(tert-Butyl)-4-(2,6-dimethoxyphenyl)-2-ethyl-2,3-dihydrobenzo[d][1,3]oxaphosphole
Brand: ChemScene
Availability: OutOfStock
Rating: 5 (1 reviews)

CAS No. 2247162-97-4
Cat. No. CS-0091110
Purity≥97%
MDL No.MFCD32641183

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(2S,3S)-3-(tert-Butyl)-4-(2,6-dimethoxyphenyl)-2-ethyl-2,3-dihydrobenzo[d][1,3]oxaphosphole|CS-0091110

Structure of 2247162-97-4

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 2247162-97-4
Cat. No. CS-0091110
Purity ≥97%
MDL No. MFCD32641183
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₁H₂₇O₃P
Molecular Weight 358.41
Synonym(s) ZJ-0143/(2S,3S)-3-(tert-butyl)-4-(2, 6-dimethoxyphenyl)-2-ethy l-2,3-dihydrobenzo[d][1,3]oxaphosphole
SMILES COC1=CC=CC(OC)=C1C2=C([P@](C(C)(C)C)[C@@H](CC)O3)C3=CC=C2

Description

This chiral phosphole features a sterically shielded tert-butyl group and a 2,6-dimethoxyphenyl moiety, enhancing stability and solubility. The dihydrobenzo[d][1,3]oxaphosphole core integrates a reactive phosphorus center suitable for asymmetric synthesis. Bench-stable under standard conditions, it enables efficient coupling reactions in catalytic applications.

Application

(2S,3S)-3-(tert-Butyl)-4-(2,6-dimethoxyphenyl)-2-ethyl-2,3-dihydrobenzo[d][1,3]oxaphosphole serves as a sterically encumbered, bench-stable phosphole derivative that functions as a versatile building block in transition-metal-catalyzed cross-coupling reactions. Its rigid chiral scaffold and electron-rich aryl moiety enable efficient Pd-catalyzed C–C and C–heteroatom bond formations, while the tert-butyl group enhances stability and simplifies purification. This compound facilitates the construction of complex heterocyclic architectures common in medicinal chemistry and materials science.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 27.69
LogP 5.405
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 4

Key Words

2247162-97-4 sigma2247162-97-4 manufacturer2247162-97-4 price2247162-97-4 structure2247162-97-4 SDSbuy 2247162-97-42247162-97-4 supplier2247162-97-4 uses2247162-97-4 molecular weightprice of 2247162-97-42247162-97-4 chemical name formula of 2247162-97-4

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(2S,3S)-3-(tert-Butyl)-4-(2,6-dimethoxyphenyl)-2-ethyl-2,3-dihydrobenzo[d][1,3]oxaphosphole

CAS No. 2247162-97-4

Recommended Products