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Methyl 6-hydroxy-2-methylpyridine-3-carboxylate

  • CAS No. 223788-08-7

  • Cat. No. CS-0217859
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 6-hydroxy-2-methylpyridine-3-carboxylate|CS-0217859

Structure of 223788-08-7

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General Information

  • CAS No. 223788-08-7
  • Cat. No. CS-0217859
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₃
  • Molecular Weight 167.16
  • Synonym(s) Methyl 2-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylate
  • SMILES CC1=NC(=CC=C1C(=O)OC)O

Synthesis

  • Route1
    • null|null
      922-67-8
    • Methyl 3-Aminobut-2-enoate Nifedipine Impurity|CS-0213998
      14205-39-1
    • ~%
    • In-stock
      Methyl 6-hydroxy-2-methylpyridine-3-carboxylate|CS-0217859
      223788-08-7

    References

    • ASTRAZENECA AB Patent: WO2008/85119 A1, 2008 ; Location in patent: Page/Page column 212 ; WO 2008/085119 A1
  • Route2
    • null|null
      67-56-1
    • In-stock
      6-Hydroxy-2-methylnicotinic acid|CS-0454762
      66909-37-3
    • ~39%
    • In-stock
      Methyl 6-hydroxy-2-methylpyridine-3-carboxylate|CS-0217859
      223788-08-7

    References

    • Quan; Wityak; Dominguez; Duncia; Kettner; Ellis; Liauw; Park; Santella; Knabb; Thoolen; Weber; Wexler Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 13 p. 1595 - 1600

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   59.42
  • LogP   0.88222
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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