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CS-W001157 4
Total: USD 88.00

(5-Chlorobenzofuran-2-yl)boronic acid

  • CAS No. 223576-64-5

  • Cat. No. CS-0157650
  • Purity≥98%
  • MDL No.MFCD18383028

*For research and further manufacturing use only, not for direct human use.

(5-Chlorobenzofuran-2-yl)boronic acid|CS-0157650

Structure of 223576-64-5

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General Information

  • CAS No. 223576-64-5
  • Cat. No. CS-0157650
  • Purity ≥98%
  • MDL No. MFCD18383028
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆BClO₃
  • Molecular Weight 196.40
  • Synonym(s) 5-chlorobenzofuran-2-boronic acid
  • SMILES C1=C(C=C2C=C(B(O)O)OC2=C1)Cl

Description

This boronate moiety integrates readily into Suzuki-Miyaura couplings, delivering functionalized heterocycles with high efficiency. The chlorinated benzofuran scaffold enhances reactivity and stability under standard conditions, enabling seamless incorporation into complex molecular architectures.

Application

(5-Chlorobenzofuran-2-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. Its stability, ease of handling, and compatibility with diverse functional groups make it well-suited for constructing complex heterocyclic architectures in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   53.6
  • LogP   0.766
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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