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Structure of 223381-58-6
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1-Benzylazetidin-3-amine features a bicyclic azetidine core fused with a benzylated amine side chain, delivering enhanced metabolic stability and improved membrane permeability. This scaffold integrates a primary amine at the 3-position with a benzylic handle, enabling direct conjugation or functionalization in bioconjugate chemistry and medicinal discovery.
1-Benzylazetidin-3-amine serves as a versatile building block for medicinal chemistry, enabling the construction of azetidine-based scaffolds prevalent in bioactive molecules. Its benzyl group enhances solubility and stability, while the primary amine facilitates straightforward functionalization via alkylation, acylation, or reductive amination. The molecule exhibits excellent bench stability and compatibility with standard purification methods, making it ideal for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: