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CS-W001157 4
Total: USD 88.00

2,6-Dimethoxypyridine-3-boronic acid

  • CAS No. 221006-70-8

  • Cat. No. CS-W000902
  • Purity≥98%
  • MDL No.MFCD03788239

*For research and further manufacturing use only, not for direct human use.

2,6-Dimethoxypyridine-3-boronic acid|CS-W000902

Structure of 221006-70-8

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General Information

  • CAS No. 221006-70-8
  • Cat. No. CS-W000902
  • Purity ≥98%
  • MDL No. MFCD03788239
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀BNO₄
  • Molecular Weight 182.97
  • Synonym(s) None
  • SMILES COC1=NC(OC)=C(B(O)O)C=C1

Application

2,6-Dimethoxypyridine-3-boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The pyridine core provides orthogonal reactivity, while the dimethoxy substituents enhance solubility and stabilize the boronic acid functionality. Its bench-stable nature and compatibility with diverse functional groups make it ideal for constructing complex heterocyclic scaffolds in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • Smith, Amy E.; Clapham, Kate M.; Batsanov, Andrei S.; Bryce, Martin R.; Tarbit, Brian European Journal of Organic Chemistry, 2008 , # 8 p. 1458 - 1463

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   71.81
  • LogP   -1.2214
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   3

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