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Structure of 1012084-56-8
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2-Methylpyridine-3-boronic acid pinacol ester features a pyridyl boronate moiety with a methyl substituent at the ortho position, offering enhanced stability and compatibility in cross-coupling reactions. The pinacol ester protects the boronic acid functionality, enabling reliable handling and shelf-stable storage under ambient conditions. This derivative facilitates efficient C–C bond formation in Suzuki-Miyaura coupling processes, particularly for heterocyclic scaffolds requiring moderate electron density and steric control.
2-Methylpyridine-3-boronic acid pinacol ester serves as a stable, bench-ready building block for palladium-catalyzed cross-coupling reactions. Its robust boronate ester functionality enables efficient Suzuki-Miyaura coupling with aryl and heteroaryl halides, facilitating the construction of biaryl and heterobiaryl scaffolds common in medicinal chemistry and materials science. The pinacol protection enhances handling and purification while maintaining high reactivity under standard conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: