Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

7,8-Dihydroisoquinolin-5(6H)-one

  • CAS No. 21917-86-2

  • Cat. No. CS-W022523
  • Purity≥96%
  • MDL No.MFCD08235026

*For research and further manufacturing use only, not for direct human use.

7,8-Dihydroisoquinolin-5(6H)-one|CS-W022523

Structure of 21917-86-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 21917-86-2
  • Cat. No. CS-W022523
  • Purity ≥96%
  • MDL No. MFCD08235026
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉NO
  • Molecular Weight 147.17
  • Synonym(s) 7,8-Dihydro-5(6H)-isoquinolinone
  • SMILES O=C1C2=C(C=NC=C2)CCC1

Description

7,8-Dihydroisoquinolin-5(6H)-one is a bench-stable heterocyclic scaffold featuring a partially saturated isoquinoline core with a ketone functionality at the 5-position. This structure integrates readily into synthetic routes for bioactive molecules, offering enhanced solubility and predictable reactivity in medicinal chemistry applications.

Application

7,8-Dihydroisoquinolin-5(6H)-one serves as a versatile scaffold in medicinal chemistry, enabling efficient access to bioactive heterocycles through standard functionalization at the carbonyl and aromatic positions. Its bench-stable nature and compatibility with common coupling and reduction protocols facilitate straightforward derivatization, making it a practical building block for target-oriented synthesis and library development.

Synthesis

  • Route1

    References

    • PALAU PHARMA, S. A. Patent: WO2007/60198 A1, 2007 ; Location in patent: Page/Page column 33 ; WO 2007/060198 A1
  • Route2

    References

    • Nicolaou; Baran; Zhong Journal of the American Chemical Society, 2001 , vol. 123, # 13 p. 3183 - 3185
  • Route3
    • In-stock
      5,6,7,8-Tetrahydroisoquinoline|CS-0114104
      36556-06-6
    • ~29%
    • 6,7-Dihydroisoquinolin-8(5H)-one|CS-0171574
      21917-88-4
    • In-stock
      7,8-Dihydroisoquinolin-5(6H)-one|CS-W022523
      21917-86-2

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 1 p. 31 - 35

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   29.96
  • LogP   1.6006
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 7,8-Dihydroisoquinolin-5(6H)-one sigma7,8-Dihydroisoquinolin-5(6H)-one manufacturer7,8-Dihydroisoquinolin-5(6H)-one price7,8-Dihydroisoquinolin-5(6H)-one structure7,8-Dihydroisoquinolin-5(6H)-one SDSbuy 7,8-Dihydroisoquinolin-5(6H)-one7,8-Dihydroisoquinolin-5(6H)-one supplier7,8-Dihydroisoquinolin-5(6H)-one uses7,8-Dihydroisoquinolin-5(6H)-one molecular weightprice of 7,8-Dihydroisoquinolin-5(6H)-one7,8-Dihydroisoquinolin-5(6H)-one chemical name formula of 7,8-Dihydroisoquinolin-5(6H)-one
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label