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CS-W001157 4
Total: USD 88.00

5,6,7,8-Tetrahydroisoquinoline

  • CAS No. 36556-06-6

  • Cat. No. CS-0114104
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5,6,7,8-Tetrahydroisoquinoline|CS-0114104

Structure of 36556-06-6

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General Information

  • CAS No. 36556-06-6
  • Cat. No. CS-0114104
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁N
  • Molecular Weight 133.19
  • Synonym(s) 4-(1-pyrrolidinyl)-1-(3-thiophenyl)-1-butanol hydrochloride
  • SMILES C12=CN=CC=C1CCCC2

Description

Reduction of 5,6,7,8-tetrahydroisoquinoline with sodium in ethanol gives trans-decahydroquinolines. 5,6,7,8-Tetrahydroisoquinoline is also referred as Bz-tetrahydroisoquinoline.5,6,7,8-Tetrahydroisoquinoline was used in total synthesis of ()-desoxycodeine-D. It was also used in the synthesis of 7,8-dihydroisoquinolin-5(6H)-one.

Synthesis

  • Route1

    References

    • Koltunov, Konstantin Yu.; Prakash, G.K. Surya; Rasul, Golam; Olah, George A. Journal of Organic Chemistry, 2007 , vol. 72, # 19 p. 7394 - 7397
  • Route2
    • 1,3-Dichloro-5,6,7,8-tetrahydroisoquinoline|CS-0619918
      38969-63-0
    • ~%
    • In-stock
      5,6,7,8-Tetrahydroisoquinoline|CS-0114104
      36556-06-6

    References

    • US2524855 , ; US2554842 , ;
  • Route3
    • null|null
      1125-99-1
    • 1,2,4-Triazine|CS-0450545
      290-38-0
    • ~40%
    • In-stock
      5,6,7,8-Tetrahydroisoquinoline|CS-0114104
      36556-06-6

    References

    • Boger, Dale L.; Panek, James S. Journal of Organic Chemistry, 1981 , vol. 46, # 10 p. 2179 - 2182

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   1.9604
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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