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Total: USD 88.00

NH-bis(C2-PEG2-NH-Boc)

  • CAS No. 2182601-69-8

  • Cat. No. CS-0108877
  • Molecule weight479.61
  • Purity≥98%
  • MDL No.MFCD31536767

*For research and further manufacturing use only, not for direct human use.

NH-bis(C2-PEG2-NH-Boc)|CS-0108877

Structure of 2182601-69-8

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General Information

  • CAS No. 2182601-69-8
  • Cat. No. CS-0108877
  • Purity ≥98%
  • MDL No. MFCD31536767
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₄₅N₃O₈
  • Molecular Weight 479.61
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCOCCOCCNCCOCCOCCNC(OC(C)(C)C)=O

Description

NH-bis(C2-PEG2-NH-Boc) features two C2-PEG2 linkers terminating in Boc-protected amines, enabling orthogonal functionalization in peptide and biomolecule conjugation. This bifunctional scaffold offers enhanced solubility and stability under standard conditions, facilitating efficient coupling reactions with minimal aggregation.

Application

NH-bis(C2-PEG2-NH-Boc) serves as a bifunctional, PEGylated linker for the synthesis of peptide-based conjugates and macrocyclic scaffolds. Its two C2-PEG2 spacers provide enhanced solubility and flexibility, while the Boc-protected amines enable orthogonal deprotection and sequential coupling. The compound demonstrates excellent bench stability, facilitates efficient purification, and functions reliably in standard amide bond formation and solid-phase synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   125.61
  • LogP   1.6918
  • H_Acceptors   9
  • H_Donors   3
  • Rotatable_Bonds   18

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