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CS-W001157 4
Total: USD 88.00

(S)-(Tetrahydrofuran-2-yl)methanamine hydrochloride

  • CAS No. 21801-94-5

  • Cat. No. CS-0438150
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-(Tetrahydrofuran-2-yl)methanamine hydrochloride|CS-0438150

Structure of 21801-94-5

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General Information

  • CAS No. 21801-94-5
  • Cat. No. CS-0438150
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂ClNO
  • Molecular Weight 137.61
  • Synonym(s) (2S)-Tetrahydro-2-furanMethanaMine Hydrochloride
  • SMILES NC[C@@H]1CCCO1.Cl

Description

(S)-(Tetrahydrofuran-2-yl)methanamine hydrochloride features a chiral tetrahydrofuran ring fused to a primary amine, delivering high enantioselectivity in asymmetric synthesis. The hydrochloride salt enhances solubility and stability under standard conditions, enabling reliable use in catalytic systems and peptide derivatization workflows.

Application

(S)-(Tetrahydrofuran-2-yl)methanamine hydrochloride serves as a chiral building block for medicinal chemistry and asymmetric synthesis, offering a rigid, enantiomerically pure tetrahydrofuran ring fused to a primary amine functionality. The hydrochloride salt enhances bench stability and solubility, facilitating straightforward handling and purification. It enables efficient access to bioactive heterocycles and peptide-like scaffolds through standard amine coupling, reductive amination, and cyclization protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   0.5459
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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