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Structure of 21683-86-3
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This 3-(1-benzofuran-2-yl)propanoic acid features a fused heterocyclic benzofuran core linked to a propanoic acid side chain, enabling direct integration into bioactive scaffolds. The electron-rich benzofuran moiety enhances π-stacking potential in target binding, while the carboxylic acid group provides a handle for derivatization.
3-(1-Benzofuran-2-yl)propanoic acid serves as a versatile building block for synthesizing bioactive heterocycles and pharmaceutical intermediates. Its conjugated aryl-alkyl carboxylic acid functionality enables direct derivatization via amide, ester, or Weinreb amide formation. The benzofuran moiety imparts structural rigidity and π-stacking potential, enhancing binding affinity in target-directed synthesis. Bench-stable and readily purified by recrystallization, it functions reliably in standard coupling protocols and is compatible with diverse reaction conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: