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Structure of 43001-25-8
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4-Iodobut-1-yne is a reactive alkyne reagent featuring a terminal triple bond and a pendant iodide. This configuration enables efficient copper-catalyzed coupling reactions, particularly in click chemistry applications. The molecule exhibits high stability under standard conditions and facilitates rapid conjugation with azide-functionalized partners, streamlining the synthesis of bioconjugates and functionalized polymers.
4-Iodobut-1-yne serves as a versatile building block in transition-metal-catalyzed coupling reactions, enabling efficient access to conjugated alkyne architectures. Its terminal alkyne functionality facilitates Sonogashira and Glaser couplings, while the iodide group provides a reliable handle for palladium-catalyzed cross-coupling transformations. The compound exhibits good bench stability and is compatible with standard purification protocols, making it a practical choice for synthesizing complex molecular scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS02,GHS05
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Signal Word : Danger
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UN#: 2924
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Class : 3,8
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Packing Group : Ⅱ
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Hazard Statements : H225-H314
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: