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CS-W001157 4
Total: USD 88.00

Pomalidomide-C4-NH2 hydrochloride

  • CAS No. 2162120-73-0

  • Cat. No. CS-0169502
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Pomalidomide-C4-NH2 hydrochloride|CS-0169502

Structure of 2162120-73-0

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General Information

  • CAS No. 2162120-73-0
  • Cat. No. CS-0169502
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₁ClN₄O₄
  • Molecular Weight 380.83
  • Synonym(s) None
  • SMILES O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCCCN)=O.[H]Cl

Application

Pomalidomide-C4-NH₂ (hydrochloride) serves as a key synthetic intermediate for the construction of immunomodulatory drug (IMiD) analogs. The C4-amino functionality enables direct conjugation via amide or urea bond formation, facilitating targeted derivatization in medicinal chemistry campaigns. Bench-stable and readily purified by standard chromatographic methods, it functions as a versatile scaffold for probing structure-activity relationships within the thalidomide-like class of compounds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   121.6
  • LogP   0.6604
  • H_Acceptors   6
  • H_Donors   3
  • Rotatable_Bonds   6

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