Lot numbers can be found on the outside label of a product:
(1-Ethyl-1H-1,2,4-triazol-5-yl)methanol
-
CAS No. 215868-81-8
- Cat. No. CS-W020499
- Purity≥98%
- MDL No.MFCD09966168
*For research and further manufacturing use only, not for direct human use.
Structure of 215868-81-8
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 215868-81-8
- Cat. No. CS-W020499
- Purity ≥98%
- MDL No. MFCD09966168
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₅H₉N₃O
- Molecular Weight 127.14
- Synonym(s) None
- SMILES OCC1=NC=NN1CC
Description
This bench-stable triazolylmethanol features a polar hydroxymethyl group flanked by an electron-rich triazole ring, enabling facile functionalization in synthetic workflows. It integrates readily into heterocyclic scaffolds and serves as a versatile handle for conjugation or derivatization under standard conditions.
Application
(1-Ethyl-1H-1,2,4-triazol-5-yl)methanol serves as a versatile building block in medicinal chemistry, enabling the synthesis of triazolyl-containing heterocycles via standard functional group transformations. The hydroxymethyl group facilitates derivatization through etherification, esterification, or oxidation to aldehyde, while the triazole ring provides metabolic stability and hydrogen-bonding capacity. Bench-stable and readily purified by chromatography, it functions effectively in multi-step syntheses and scale-up processes.
Synthesis
-
Route1
-
1034197-43-7 -
1034197-44-8
- ~%
-
In-stock
215868-81-8
-
1034197-45-9
References
-
WO2008/74991 A1, ; Page/Page column 53 ;
-
-
Route2
-
16778-70-4 -
68-12-2
- ~%
-
In-stock
215868-81-8
References
-
Carling, Robert W.; Madin, Andrew; Guiblin, Alec; Russell, Michael G. N.; Moore, Kevin W.; Mitchinson, Andrew; Sohal, Bindi; Pike, Andrew; Cook, Susan M.; Ragan, Ian C.; McKernan, Ruth M.; Quirk, Kathleen; Ferris, Pushpinder; Marshall, George; Thompson, Sally Ann; Wafford, Keith A.; Dawson, Gerard R.; Atack, John R.; Harrison, Timothy; Castro, Jose L.; Street, Leslie J. Journal of Medicinal Chemistry, 2005 , vol. 48, # 23 p. 7089 - 7092
-
-
Route3
-
16778-70-4
-
50-00-0
- ~%
-
In-stock
215868-81-8
References
-
WO2011/5520 A1, ; Page/Page column 32 ; WO 2011/005520 A1
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 50.94
- LogP -0.2097
- H_Acceptors 4
- H_Donors 1
- Rotatable_Bonds 2
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- (1-Ethyl-1H-1,2,4-triazol-5-yl)methanol sigma(1-Ethyl-1H-1,2,4-triazol-5-yl)methanol manufacturer(1-Ethyl-1H-1,2,4-triazol-5-yl)methanol price(1-Ethyl-1H-1,2,4-triazol-5-yl)methanol structure(1-Ethyl-1H-1,2,4-triazol-5-yl)methanol SDSbuy (1-Ethyl-1H-1,2,4-triazol-5-yl)methanol(1-Ethyl-1H-1,2,4-triazol-5-yl)methanol supplier(1-Ethyl-1H-1,2,4-triazol-5-yl)methanol uses(1-Ethyl-1H-1,2,4-triazol-5-yl)methanol molecular weightprice of (1-Ethyl-1H-1,2,4-triazol-5-yl)methanol(1-Ethyl-1H-1,2,4-triazol-5-yl)methanol chemical name formula of (1-Ethyl-1H-1,2,4-triazol-5-yl)methanol