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Potassium trifluoro(2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)borate

  • CAS No. 1408168-76-2

  • Cat. No. CS-0155242
  • Purity≥97%
  • MDL No.MFCD22684702

*For research and further manufacturing use only, not for direct human use.

Potassium trifluoro(2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)borate|CS-0155242

Structure of 1408168-76-2

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General Information

  • CAS No. 1408168-76-2
  • Cat. No. CS-0155242
  • Purity ≥97%
  • MDL No. MFCD22684702
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃BF₃KO₂
  • Molecular Weight 236.08
  • Synonym(s) Potassium 2-(tetrahydro-2H-pyran-2-yloxy)ethyltrifluoroborate
  • SMILES C1CCOC(C1)OCC[B-](F)(F)F.[K+]

Description

Potassium trifluoro(2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)borate delivers a stable, moisture-tolerant boron source for cross-coupling reactions. The tetrahydro-2H-pyran-2-yl protecting group ensures enhanced shelf life and ease of handling. This reagent integrates smoothly into palladium-catalyzed transformations, enabling efficient C–C bond formation under mild conditions.

Application

Potassium trifluoro(2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)borate serves as a stable, bench-ready boron reagent enabling efficient Suzuki-Miyaura cross-coupling reactions. The tetrahydro-2H-pyran-2-yl ether protecting group ensures high functional group tolerance and compatibility with diverse substrates, facilitating selective C–C bond formation under mild conditions. Its robustness simplifies purification and handling, making it ideal for iterative synthesis of complex molecular architectures in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   -0.619
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   4

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