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CS-W001157 4
Total: USD 88.00

Boc-Tyr(Bzl)-OH

  • CAS No. 2130-96-3

  • Cat. No. CS-W011789
  • Purity≥97%
  • MDL No.MFCD00065597

*For research and further manufacturing use only, not for direct human use.

Boc-Tyr(Bzl)-OH|CS-W011789

Structure of 2130-96-3

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General Information

  • CAS No. 2130-96-3
  • Cat. No. CS-W011789
  • Purity ≥97%
  • MDL No. MFCD00065597
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₅NO₅
  • Molecular Weight 371.43
  • Synonym(s) None
  • SMILES O=C([C@@H](NC(OC(C)(C)C)=O)CC1=CC=C(OCC2=CC=CC=C2)C=C1)O

Description

Boc-Tyr(Bzl)-OH is a protected tyrosine derivative featuring a benzyloxycarbonyl group on the amine and a benzyl ester on the carboxylate. This dual protection enables stable incorporation into peptide synthesis workflows, where the Boc group facilitates selective deprotection under mild acidic conditions. The benzyl ester resists premature hydrolysis, enhancing handling and storage stability. This derivative streamlines sequence assembly in solid-phase peptide synthesis.

Synthesis

  • Route1
    • In-stock
      (S)-2-((tert-Butoxycarbonyl)amino)-3-(4-hydroxyphenyl)propanoic acid|CS-W014008
      3978-80-1
    • null|null
      100-39-0
    • ~95%
    • In-stock
      Boc-Tyr(Bzl)-OH|CS-W011789
      2130-96-3

    References

    • AJINOMOTO, CO., INC. Patent: US2005/283021 A1, 2005 ; Location in patent: Page/Page column 6 ;
  • Route2
    • In-stock
      (S)-2-((tert-Butoxycarbonyl)amino)-3-(4-hydroxyphenyl)propanoic acid|CS-W014008
      3978-80-1
    • null|null
      100-44-7
    • ~81%
    • In-stock
      Boc-Tyr(Bzl)-OH|CS-W011789
      2130-96-3

    References

    • AJINOMOTO, CO., INC. Patent: US2005/283021 A1, 2005 ; Location in patent: Page/Page column 6 ;
  • Route3
    • In-stock
      Di-tert-butyl dicarbonate|CS-0017817
      24424-99-5
    • null|null
      100-39-0
    • L-Tyrosine Levodopa Impurity|CS-0229709
      60-18-4
    • ~80%
    • In-stock
      Boc-Tyr(Bzl)-OH|CS-W011789
      2130-96-3

    References

    • Shanghai Institute Of Materia Medica Chinese Academy of Sciences Patent: EP2133342 A1, 2009 ; Location in patent: Page/Page column 32 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   3.786
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   7

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