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CS-W001157 4
Total: USD 88.00

N-Boc-O-benzyl-D-tyrosine

  • CAS No. 63769-58-4

  • Cat. No. CS-0128339
  • Purity≥98%
  • MDL No.MFCD00038249

*For research and further manufacturing use only, not for direct human use.

N-Boc-O-benzyl-D-tyrosine|CS-0128339

Structure of 63769-58-4

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General Information

  • CAS No. 63769-58-4
  • Cat. No. CS-0128339
  • Purity ≥98%
  • MDL No. MFCD00038249
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₅NO₅
  • Molecular Weight 371.43
  • Synonym(s) O-benzyl-N-(tert-butoxycarbonyl)-D-tyrosine
  • SMILES O=C(O)[C@@H](CC1=CC=C(OCC2=CC=CC=C2)C=C1)NC(OC(C)(C)C)=O

Description

N-Boc-O-benzyl-D-tyrosine features a protected D-amino acid scaffold with orthogonal functionality: the Boc group ensures facile deprotection under mild acidic conditions, while the benzyl ether stabilizes the phenolic hydroxyl. This combination enables reliable incorporation into peptide sequences and synthetic intermediates requiring selective manipulation.

Synthesis

  • Route1
    • null|null
      100-39-0
    • In-stock
      N-tert-Butoxycarbonyl-D-tyrosine methyl ester|CS-M3313
      76757-90-9
    • ~73%
    • In-stock
      N-Boc-O-benzyl-D-tyrosine|CS-0128339
      63769-58-4

    References

    • Journal of Medicinal Chemistry, , vol. 25, # 1 p. 45 - 50
  • Route2

    References

    • Tetrahedron, , vol. 48, # 40 p. 8601 - 8614
  • Route3
    • null|null
      100-39-0
    • ~%
    • In-stock
      N-Boc-O-benzyl-D-tyrosine|CS-0128339
      63769-58-4

    References

    • Tetrahedron, , vol. 48, # 40 p. 8601 - 8614

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   3.786
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   7

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