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CS-W001157 4
Total: USD 88.00

2-Oxoimidazolidine-4-carboxylic acid

  • CAS No. 21277-16-7

  • Cat. No. CS-0062204
  • Purity≥95%
  • MDL No.MFCD00005258

*For research and further manufacturing use only, not for direct human use.

2-Oxoimidazolidine-4-carboxylic acid|CS-0062204

Structure of 21277-16-7

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General Information

  • CAS No. 21277-16-7
  • Cat. No. CS-0062204
  • Purity ≥95%
  • MDL No. MFCD00005258
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆N₂O₃
  • Molecular Weight 130.10
  • Synonym(s) 2-oxo-4-imidazolinecarboxylic acid
  • SMILES O=C(O)C1NC(NC1)=O

Description

This imidazolidine derivative features a carbonyl group at the 2-position and a carboxylic acid at the 4-position, creating a rigid, electron-deficient heterocyclic scaffold. The molecule integrates readily into peptide mimetics and bioactive small molecules, offering enhanced metabolic stability and predictable conformational behavior in synthetic applications.

Application

2-Oxoimidazolidine-4-carboxylic acid serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of biologically relevant scaffolds. Its functional group array—comprising a carbonyl at C2 and a carboxylic acid at C4—facilitates diverse transformations including amidation, reduction, and cyclization. The molecule exhibits bench stability and compatibility with standard purification methods, making it suitable for multi-step syntheses and process-scale applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   78.43
  • LogP   -1.2476
  • H_Acceptors   2
  • H_Donors   3
  • Rotatable_Bonds   1

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