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CS-W001157 4
Total: USD 88.00

5-(Pyridin-3-yl)-1,2-oxazole-3-carboxylic acid

  • CAS No. 893638-39-6

  • Cat. No. CS-0070507
  • Purity≥95%
  • MDL No.MFCD07377114

*For research and further manufacturing use only, not for direct human use.

5-(Pyridin-3-yl)-1,2-oxazole-3-carboxylic acid|CS-0070507

Structure of 893638-39-6

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General Information

  • CAS No. 893638-39-6
  • Cat. No. CS-0070507
  • Purity ≥95%
  • MDL No. MFCD07377114
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆N₂O₃
  • Molecular Weight None
  • Synonym(s) 5-(3-Pyridyl)isoxazole-3-carboxylic Acid
  • SMILES O=C(O)C1=NOC(C2=CC=CN=C2)=C1

Description

5-(Pyridin-3-yl)-1,2-oxazole-3-carboxylic acid features a pyridyl moiety fused to an electron-deficient oxazole ring, enabling strong hydrogen bonding and dipole interactions. This scaffold delivers enhanced solubility and metabolic stability in bioactive molecule design. The carboxylic acid group facilitates conjugation and derivatization under standard coupling conditions.

Application

5-(Pyridin-3-yl)-1,2-oxazole-3-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to bioactive scaffolds through standard coupling and functionalization reactions. Its pyridyl-substituted oxazole core offers enhanced solubility and metabolic stability, while the carboxylic acid group facilitates direct derivatization or amide formation in peptide and macrocycle assembly. Bench-stable and readily purified by recrystallization, it functions reliably in medicinal chemistry campaigns and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   76.22
  • LogP   1.4348
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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