N4-Trityl-L-asparagine hydrate

Name: N4-Trityl-L-asparagine hydrate
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CAS No. 210824-10-5
Cat. No. CS-0527005
Molecule weight392.45
Purity≥97%
MDL No.None

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Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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N4-Trityl-L-asparagine hydrate|CS-0527005

Structure of 210824-10-5

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General Information

CAS No. 210824-10-5
Cat. No. CS-0527005
Purity ≥97%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₃H₂₄N₂O₄
Molecular Weight 392.45
Synonym(s) L-ASPARAGINE(TRITYL) H2O
SMILES OC([C@@H](N)CC(NC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=O)=O.O

Description

N4-Trityl-L-asparagine (hydrate) features a trityl group strategically protecting the α-amino functionality of asparagine, enabling selective coupling in peptide synthesis. This bench-stable derivative simplifies handling and purification, while the hydrate form enhances solubility in organic solvents. The protected side chain remains intact, allowing orthogonal deprotection strategies in complex sequence assembly.

Application

N4-Trityl-L-asparagine (hydrate) serves as a protected amino acid building block for peptide synthesis, offering stable amide protection at the side-chain amine. The trityl group provides high orthogonality and ease of removal under mild acidic conditions, enabling selective deprotection during complex sequence assembly. Its crystalline hydrate form enhances handling and storage stability, while maintaining compatibility with standard coupling protocols and diverse functional group environments encountered in synthetic peptide workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

TPSA 123.92
LogP 2.072
H_Acceptors 3
H_Donors 3
Rotatable_Bonds 7

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Asparagine and derivatives

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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N4-Trityl-L-asparagine hydrate

CAS No. 210824-10-5

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