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(R)-2-(Aminomethyl)-3-methylbutanoic acid

  • CAS No. 210345-86-1

  • Cat. No. CS-0061014
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-2-(Aminomethyl)-3-methylbutanoic acid|CS-0061014

Structure of 210345-86-1

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General Information

  • CAS No. 210345-86-1
  • Cat. No. CS-0061014
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO₂
  • Molecular Weight 131.17
  • Synonym(s) (R)-β2homovaline
  • SMILES CC(C)[C@H](CN)C(=O)O

Description

(R)-2-(Aminomethyl)-3-methylbutanoic acid features a chiral α-amino acid scaffold with a branched alkyl side chain, delivering enhanced metabolic stability and favorable solubility for peptide conjugation. This stereodefined building block integrates efficiently into bioactive peptide architectures, enabling precise control over conformation and receptor interaction in drug discovery applications.

Application

(R)-2-(Aminomethyl)-3-methylbutanoic acid serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through standard amide and ester formation. Its well-defined stereochemistry and bench-stable carboxylic acid functionality facilitate straightforward derivatization, purification, and incorporation into peptidomimetics or drug candidates requiring branched aliphatic side chains.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   0.3019
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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