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(S)-2-(((tert-Butoxycarbonyl)amino)methyl)-3-methylbutanoic acid

  • CAS No. 210346-16-0

  • Cat. No. CS-0060834
  • Molecule weight231.29
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-2-(((tert-Butoxycarbonyl)amino)methyl)-3-methylbutanoic acid|CS-0060834

Structure of 210346-16-0

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General Information

  • CAS No. 210346-16-0
  • Cat. No. CS-0060834
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₁NO₄
  • Molecular Weight 231.29
  • Synonym(s) (2S)-2-{[(tert-Butoxycarbonyl)amino]-methyl}-3-methylbutanoic acid
  • SMILES CC([C@H](C(O)=O)CNC(OC(C)(C)C)=O)C

Description

(S)-2-(((tert-Butoxycarbonyl)amino)methyl)-3-methylbutanoic acid features a chiral α-amino acid backbone with a protected amine and hydrophobic side chain. This bench-stable building block integrates seamlessly into peptide synthesis workflows, enabling efficient access to complex peptidomimetics and bioactive scaffolds under standard conditions.

Application

(S)-2-(((tert-Butoxycarbonyl)amino)methyl)-3-methylbutanoic acid serves as a valuable chiral building block in peptide synthesis, enabling the construction of sterically hindered amino acid motifs. The tert-butyl ester and carbamate groups provide orthogonal protection for carboxylic acid and amine functionalities, facilitating sequential coupling reactions. Its bench-stable nature and compatibility with standard deprotection protocols make it well-suited for multi-step synthetic sequences in medicinal chemistry and API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   1.8679
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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