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(R)-6,7-Dihydro-5H-cyclopenta[b]pyridine-2,5-diamine dihydrochloride

  • CAS No. 2101848-16-0

  • Cat. No. CS-0069944
  • Molecule weight222.11
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-6,7-Dihydro-5H-cyclopenta[b]pyridine-2,5-diamine dihydrochloride|CS-0069944

Structure of 2101848-16-0

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General Information

  • CAS No. 2101848-16-0
  • Cat. No. CS-0069944
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₃Cl₂N₃
  • Molecular Weight 222.11
  • Synonym(s) None
  • SMILES N[C@H](CC1)C2=C1N=C(N)C=C2.Cl.Cl

Description

(R)-6,7-Dihydro-5H-cyclopenta[b]pyridine-2,5-diamine dihydrochloride is a stereochemically defined heterocyclic amine featuring two primary amine groups flanking a saturated cyclopenta ring fused to pyridine. This bench-stable salt form enhances solubility and handling in aqueous reaction media, enabling efficient incorporation into bioactive molecule scaffolds and medicinal chemistry campaigns.

Application

(R)-6,7-Dihydro-5H-cyclopenta[b]pyridine-2,5-diamine dihydrochloride serves as a versatile chiral building block for the synthesis of bioactive heterocycles. Its diamine functionality enables straightforward functionalization via alkylation, acylation, and transition-metal-catalyzed coupling reactions. The compound exhibits excellent bench stability and facilitates purification due to its salt form, making it well-suited for medicinal chemistry campaigns targeting CNS-active compounds and kinase inhibitors.

Safety Information

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Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   64.93
  • LogP   1.4534
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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