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CS-W001157 4
Total: USD 88.00

(R)-1-(6-Bromopyridin-3-yl)ethanamine

  • CAS No. 1212942-90-9

  • Cat. No. CS-0101414
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-1-(6-Bromopyridin-3-yl)ethanamine|CS-0101414

Structure of 1212942-90-9

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General Information

  • CAS No. 1212942-90-9
  • Cat. No. CS-0101414
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉BrN₂
  • Molecular Weight 201.06
  • Synonym(s) None
  • SMILES C[C@@H](N)C1=CC=C(Br)N=C1

Description

(R)-1-(6-Bromopyridin-3-yl)ethanamine features a chiral ethylamine handle attached to a brominated pyridine ring, enabling selective coupling in asymmetric synthesis. The para-bromo substituent provides a reactive handle for cross-coupling transformations, while the (R)-stereochemistry ensures high enantioselectivity in downstream applications. This bench-stable, moisture-tolerant amine integrates efficiently into complex molecular architectures.

Application

(R)-1-(6-Bromopyridin-3-yl)ethanamine serves as a versatile chiral building block for the synthesis of pyridine-containing pharmaceutical intermediates. Its bromo group enables palladium-catalyzed coupling reactions, while the chiral amine functionality provides stereochemical control in target-directed synthesis. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in medicinal chemistry campaigns requiring stereoselective heterocyclic scaffold assembly.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.8638
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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