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CS-W001157 4
Total: USD 88.00

6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carboxylic acid

  • CAS No. 2089381-00-8

  • Cat. No. CS-0138354
  • Purity≥98%
  • MDL No.MFCD30529017
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carboxylic acid|CS-0138354

Structure of 2089381-00-8

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Description

6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carboxylic acid features a fused heterocyclic core bearing bromo and methoxy substituents at electron-rich positions, enabling direct functionalization in cross-coupling reactions. The carboxylic acid group provides a handle for amide bond formation or salt generation, enhancing solubility and bioavailability. This scaffold exhibits stability under standard reaction conditions, facilitating use in medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.

Application

6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carboxylic acid serves as a versatile building block for the synthesis of biologically active heterocycles. Its bromo and carboxylic acid functionalities enable palladium-catalyzed cross-coupling and derivatization reactions, while the methoxy group provides orthogonal reactivity. The molecule exhibits good bench stability and facilitates efficient purification, making it well-suited for medicinal chemistry campaigns and API intermediate development.

General Information

  • CAS No. 2089381-00-8
  • Cat. No. CS-0138354
  • Purity ≥98%
  • MDL No. MFCD30529017
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇BrN₂O₃
  • Molecular Weight 271.07
  • Synonym(s) None
  • SMILES O=C(C1=C2C(OC)=CC(Br)=CN2N=C1)O

Computational Chemistry Data

  • TPSA   63.83
  • LogP   1.8036
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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