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CS-W001157 4
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Ethyl 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carboxylate

  • CAS No. 1207557-35-4

  • Cat. No. CS-0041099
  • Purity≥95%
  • MDL No.MFCD17926418

*For research and further manufacturing use only, not for direct human use.

Ethyl 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carboxylate|CS-0041099

Structure of 1207557-35-4

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General Information

  • CAS No. 1207557-35-4
  • Cat. No. CS-0041099
  • Purity ≥95%
  • MDL No. MFCD17926418
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₁BrN₂O₃
  • Molecular Weight 299.12
  • Synonym(s) None
  • SMILES O=C(C1=C2C(OC)=CC(Br)=CN2N=C1)OCC

Description

Ethyl 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carboxylate features a brominated pyrazolopyridine core with orthogonal functional handles: a methoxy group enhancing solubility and an ethyl ester enabling downstream derivatization. This bench-stable scaffold integrates readily into transition-metal-catalyzed coupling processes and serves as a key intermediate in the synthesis of bioactive heterocycles.

Application

Ethyl 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carboxylate serves as a versatile building block for the synthesis of pyrazolopyridine-based scaffolds. Its bromo group enables palladium-catalyzed cross-coupling reactions, while the ester and methoxy functionalities offer orthogonal handles for further derivatization. The compound exhibits good bench stability and facilitates efficient functionalization in standard medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.83
  • LogP   2.2821
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   3

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