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CS-W001157 4
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2-Amino-3-methyl-3-phenylbutanoic acid hydrochloride

  • CAS No. 2089291-82-5

  • Cat. No. CS-0200335
  • Molecule weight229.70
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Amino-3-methyl-3-phenylbutanoic acid hydrochloride|CS-0200335

Structure of 2089291-82-5

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General Information

  • CAS No. 2089291-82-5
  • Cat. No. CS-0200335
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆ClNO₂
  • Molecular Weight 229.70
  • Synonym(s) None
  • SMILES O=C(C(C(C)(C)C1=CC=CC=C1)N)O.Cl

Description

This hydrochloride salt of 2-amino-3-methyl-3-phenylbutanoic acid features a sterically hindered α-carbon and a benzylic chiral center, enabling its use in asymmetric synthesis. The protonated amine enhances solubility in aqueous media while maintaining stability under standard bench conditions.

Application

2-Amino-3-methyl-3-phenylbutanoic acid hydrochloride serves as a valuable chiral building block for the synthesis of biologically relevant heterocycles and amino acid derivatives. Its well-defined stereochemistry and stable hydrochloride salt form facilitate handling, purification, and incorporation into peptide and non-peptidic scaffolds. The molecule enables efficient access to substituted pyrrolidines and piperidines via cyclization reactions, with broad compatibility in standard coupling and functional group transformation protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.7979
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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