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CS-W001157 4
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Acid-PEG1-C2-Boc

  • CAS No. 2086689-08-7

  • Cat. No. CS-0114713
  • Purity≥98%
  • MDL No.MFCD30723273

*For research and further manufacturing use only, not for direct human use.

Acid-PEG1-C2-Boc|CS-0114713

Structure of 2086689-08-7

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General Information

  • CAS No. 2086689-08-7
  • Cat. No. CS-0114713
  • Purity ≥98%
  • MDL No. MFCD30723273
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₈O₅
  • Molecular Weight 218.25
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)CCOCCC(O)=O

Description

Acid-PEG1-C2-Boc features a carboxylic acid terminus linked via a short PEG spacer to a C2 alkyl chain bearing a Boc protecting group. This design enables selective conjugation under mild conditions, with the Boc moiety offering stable protection until deprotection. The molecule combines solubility from the PEG unit with orthogonal reactivity for bioconjugation workflows.

Application

Acid-PEG1-C2-Boc serves as a versatile, bench-stable building block for the synthesis of PEGylated compounds and bioconjugates. Its carboxylic acid functionality enables efficient coupling with amines under standard conditions, while the Boc group provides orthogonal protection for amine intermediates. The PEG1 spacer enhances solubility and reduces aggregation in aqueous environments, facilitating purification and downstream applications in peptide modification and drug delivery systems.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   72.83
  • LogP   1.2095
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   6

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