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CS-W001157 4
Total: USD 88.00

(S)-2-Amino-3-(4-nitrophenyl)propanoic acid hydrate

  • CAS No. 207591-86-4

  • Cat. No. CS-W010409
  • Purity≥98%
  • MDL No.MFCD00150543

*For research and further manufacturing use only, not for direct human use.

(S)-2-Amino-3-(4-nitrophenyl)propanoic acid hydrate|CS-W010409

Structure of 207591-86-4

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General Information

  • CAS No. 207591-86-4
  • Cat. No. CS-W010409
  • Purity ≥98%
  • MDL No. MFCD00150543
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂N₂O₅
  • Molecular Weight 228.20
  • Synonym(s) None
  • SMILES N[C@@H](CC1=CC=C([N+]([O-])=O)C=C1)C(O)=O.[H]O[H]

Description

(S)-2-Amino-3-(4-nitrophenyl)propanoic acid hydrate is a chiral building block featuring a para-nitro-substituted phenyl group and a stereogenic center. This bench-stable, moisture-tolerant amino acid derivative integrates readily into peptide synthesis workflows, offering high compatibility with standard coupling protocols and enabling access to bioactive analogs in medicinal chemistry applications.

Application

(S)-2-Amino-3-(4-nitrophenyl)propanoic acid hydrate serves as a key chiral building block for the synthesis of β-amino acids and pharmaceutically relevant heterocycles. Its well-defined stereochemistry enables stereoselective transformations, while the ortho-directing nitro group facilitates downstream functionalization. The hydrate form enhances bench stability and simplifies handling, making it suitable for peptide coupling, catalytic reduction, and transition-metal-catalyzed cross-coupling reactions in medicinal chemistry workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   137.96
  • LogP   -0.2755
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

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