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CS-W001157 4
Total: USD 88.00

Boc-N-Me-Leu-OH

  • CAS No. 53363-89-6

  • Cat. No. CS-W010250
  • Purity≥97%
  • MDL No.MFCD00038522

*For research and further manufacturing use only, not for direct human use.

Boc-N-Me-Leu-OH|CS-W010250

Structure of 53363-89-6

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General Information

  • CAS No. 53363-89-6
  • Cat. No. CS-W010250
  • Purity ≥97%
  • MDL No. MFCD00038522
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₃NO₄
  • Molecular Weight 245.32
  • Synonym(s) None
  • SMILES CC(C)C[C@H](N(C(OC(C)(C)C)=O)C)C(O)=O

Description

Boc-N-Me-Leu-OH serves as a protected leucine derivative featuring a tert-butoxycarbonyl group at the N-terminus and a methyl substitution on the nitrogen. This configuration enhances stability during peptide synthesis, enabling efficient incorporation into oligopeptide sequences under standard conditions. The molecule resists racemization and maintains integrity in both solution-phase and solid-phase workflows.

Synthesis

  • Route1
    • In-stock
      Boc-L-Leu-OH|CS-W020087
      13139-15-6
    • null|null
      74-88-4
    • ~94%
    • In-stock
      Boc-N-Me-Leu-OH|CS-W010250
      53363-89-6

    References

    • Bossler, Hans G.; Seebach, Dieter Helvetica Chimica Acta, 1994 , vol. 77, # 4 p. 1124 - 1165
  • Route2
    • In-stock
      Boc-L-Leu-OH|CS-W020087
      13139-15-6
    • null|null
      77-78-1
    • ~91%
    • In-stock
      Boc-N-Me-Leu-OH|CS-W010250
      53363-89-6

    References

    • Prashad, Mahavir; Har, Denis; Hu, Bin; Kim, Hong-Yong; Repic, Oljan; Blacklock, Thomas J Organic letters, 2003 , vol. 5, # 2 p. 125 - 128
  • Route3
    • null|null
      130994-88-6
    • ~%
    • In-stock
      Boc-N-Me-Leu-OH|CS-W010250
      53363-89-6

    References

    • Journal of Natural Products, , vol. 74, # 4 p. 882 - 887

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   2.3526
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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