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CS-W001157 4
Total: USD 88.00

H-DL-Phe(4-NO2)-OH

  • CAS No. 2922-40-9

  • Cat. No. CS-W015121
  • Purity≥98%
  • MDL No.MFCD00007384

*For research and further manufacturing use only, not for direct human use.

H-DL-Phe(4-NO2)-OH|CS-W015121

Structure of 2922-40-9

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General Information

  • CAS No. 2922-40-9
  • Cat. No. CS-W015121
  • Purity ≥98%
  • MDL No. MFCD00007384
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀N₂O₄
  • Molecular Weight 210.19
  • Synonym(s) None
  • SMILES NC(C(O)=O)CC1=CC=C([N+]([O-])=O)C=C1

Description

H-DL-Phe(4-NO2)-OH features a para-nitro-substituted phenylalanine scaffold with enhanced electron-withdrawing character, enabling precise tuning of reactivity in peptide synthesis. This bench-stable derivative integrates readily into complex sequences under standard conditions, offering improved solubility and compatibility in aqueous and organic media.

Application

H-DL-Phe(4-NO₂)-OH serves as a versatile building block for peptide synthesis, enabling the incorporation of a para-nitrophenylalanine residue with defined stereochemistry. The nitro group provides a robust handle for downstream transformations, including reduction to an amino group or participation in metal-catalyzed coupling reactions. Its stability under standard peptide coupling conditions and compatibility with common protecting group strategies make it a practical choice for synthesizing functionalized peptides and heterocyclic scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   106.46
  • LogP   0.5492
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

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