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CS-W001157 4
Total: USD 88.00

4-Bromopyrazole

  • CAS No. 2075-45-8

  • Cat. No. CS-W009265
  • Purity≥97%
  • MDL No.MFCD00075602

*For research and further manufacturing use only, not for direct human use.

4-Bromopyrazole|CS-W009265

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General Information

  • CAS No. 2075-45-8
  • Cat. No. CS-W009265
  • Purity ≥97%
  • MDL No. MFCD00075602
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₃BrN₂
  • Molecular Weight 146.97
  • Synonym(s) None
  • SMILES BrC1=CNN=C1

Description

4-Bromopyrazole is a heteroaryl halide and its cyanation in the presence of palladium catalysts has been reported.4-Bromopyrazole may be used in the preparation of 4-bromo-1-(2-chloroethyl)-1H-pyrazole. It may be used as starting material in the synthesis of 1,4-bipyrazoles.

Synthesis

  • Route1

    References

    • BRISTOL-MYERS SQUIBB COMPANY; MOSLIN, Ryan M.; WEINSTEIN, David S.; WROBLESKI, Stephen T.; TOKARSKI, John S.; KUMAR, Amit Patent: WO2014/74661 A1, 2014 ; Location in patent: Paragraph 00249 ;
  • Route2

    References

    • Chemische Berichte, , vol. 28, p. 688 Journal fuer Praktische Chemie (Leipzig), , vol. <2> 53, p. 127
  • Route3

    References

    • Russian Journal of General Chemistry, , vol. 77, # 9 p. 1652 - 1653

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   1.1722
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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