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CS-W001157 4
Total: USD 88.00

1H-pyrazole

  • CAS No. 288-13-1

  • Cat. No. CS-W008829
  • Purity≥97%
  • MDL No.MFCD00005234

*For research and further manufacturing use only, not for direct human use.

1H-pyrazole|CS-W008829

Structure of 288-13-1

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General Information

  • CAS No. 288-13-1
  • Cat. No. CS-W008829
  • Purity ≥97%
  • MDL No. MFCD00005234
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₄N₂
  • Molecular Weight 68.08
  • Synonym(s) Pyrazole
  • SMILES N1=CC=CN1

Description

5-Fluorouridine is a modified uridine nucleoside with a fluorine atom at position 5 of the uracil. 5-Fluorouridine is a highly cytotoxic metabolite of 5-fluorouracil, a drug used to treat a variety of cancers, on the market with the trade name Adrucil.

Synthesis

  • Route1
    • null|null
      40797-97-5
    • In-stock
      2,6-Dichlorophenylhydrazine hydrochloride|CS-W014962
      50709-36-9
    • ~61%
    • In-stock
      1H-pyrazole|CS-W008829
      288-13-1

    References

    • GPC Biotech, Inc.; GPC Biotech AG Patent: US2004/266854 A1, 2004 ; US 20040266854 A1
  • Route2

    References

    • Wang, Jia; Liang, Yan-Liang; Qu, Jin Chemical Communications, 2009 , # 34 p. 5144 - 5146
  • Route3
    • 2-Pyrazoline|CS-0205014
      109-98-8
    • ~%
    • In-stock
      1H-pyrazole|CS-W008829
      288-13-1

    References

    • Bayer Aktiengesellschaft Patent: US4434292 A1, 1984 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06,GHS08
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302-H311-H315-H318-H373-H412
Precautionary Statements : P260-P264-P270-P273-P280-P302+P352-P330-P361+P364-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   0.4097
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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