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CS-W001157 4
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(R)-2-((tert-Butoxycarbonyl)amino)-3-(3-cyanophenyl)propanoic acid

  • CAS No. 205445-56-3

  • Cat. No. CS-W010003
  • Purity≥97%
  • MDL No.MFCD00797561

*For research and further manufacturing use only, not for direct human use.

(R)-2-((tert-Butoxycarbonyl)amino)-3-(3-cyanophenyl)propanoic acid|CS-W010003

Structure of 205445-56-3

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General Information

  • CAS No. 205445-56-3
  • Cat. No. CS-W010003
  • Purity ≥97%
  • MDL No. MFCD00797561
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₈N₂O₄
  • Molecular Weight 290.31
  • Synonym(s) Boc-3-cyano-D-phenylalanine
  • SMILES O=C(O)[C@@H](CC1=CC=CC(C#N)=C1)NC(OC(C)(C)C)=O

Description

This chiral building block features a protected amino group and a para-cyano-substituted phenyl moiety, enabling direct incorporation into peptide architectures. The tert-butyl carbamate handle ensures stability during synthesis, while the electron-withdrawing nitrile group enhances reactivity in downstream transformations.

Application

(R)-2-((tert-Butoxycarbonyl)amino)-3-(3-cyanophenyl)propanoic acid serves as a valuable chiral building block in peptide and heterocyclic synthesis, enabling efficient access to bioactive scaffolds. The Boc-protected amine and pendant nitrile group offer orthogonal reactivity for selective transformations. Its bench-stable nature and compatibility with standard coupling conditions facilitate straightforward purification and integration into complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   99.42
  • LogP   2.07868
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

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