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Structure of 20200-22-0
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N-Methyl-2-nitro-4-(trifluoromethyl)aniline features a strongly electron-deficient aromatic core enhanced by the nitro and trifluoromethyl groups, enabling efficient coupling in cross-coupling reactions. The N-methyl substituent improves solubility and stability under standard conditions, facilitating use in synthetic transformations requiring robustness and controlled reactivity.
N-Methyl-2-nitro-4-(trifluoromethyl)aniline serves as a versatile building block in medicinal chemistry, enabling the synthesis of trifluoromethylated heterocycles and bioactive scaffolds. Its nitro group facilitates efficient reduction to an amine, while the trifluoromethyl moiety enhances metabolic stability and lipophilicity. The N-methyl substitution improves solubility and reduces basicity, offering favorable handling properties and compatibility with standard coupling reactions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H317-H319
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Precautionary Statements : P261-P264-P272-P280-P302+P352-P362+P364-P501
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Lot numbers can be found on the outside label of a product: